We are a synthetic polymer chemistry group based in the Department of Chemistry, University of Sheffield, UK. Our research is diverse but may be loosely grouped as novel materials for therapeutics and diagnostics.

To achieve this we use a combination of "small molecule" synthesis, modern polymer synthesis, including controlled radical and ring-opening polymerizations, and in vitro and in vivo pre-clinical studies.

Current projects range from embolizing agents and trandermal drug delivery to industrial coatings. Further details can be found on our research pages or individual group member pages.

slide show image 1: 3D render of DNA based micelles in blood slide show image 2: FRET data for the unpacking of DNA micelles slide show image 3: 3D render of temperature responsive particles slide show image 4: Confocal microscopy image of cells treated with fluorescent polymer


Recent Papers

  • "Self-assembly of amphiphilic statistical copolymers and their aqueous rheological properties", Macromolecules, 2018, 51, 1474-1487. [DOI]
  • "Alkyl-modified oligonucleotides as intercalating vehicles for doxorubicin uptake via albumin binding", Mol. Pharmaceutics, 2018, 15, 437-446. [DOI]
  • "Control of aggregation temperatures in mixed and blended cytocompatible thermoresponsive block co-polymer nanoparticles", Soft Matter, 2017, 13, 7441-7452. [DOI]
  • "The effect of hyperbranched poly(acrylic acid)s on the morphology and size of precipitated nanoscale (fluor)hydroxyapatite.", J. Mater. Chem. B., 2017, 5, 6027-6033. [DOI]
  • "Influence of polymer size on uptake and cytotoxicity of doxorubicin-loaded DNA–PEG conjugates", Bioconjugate Chem., 2016, 27, 1244-1252. [DOI]
  • Full publication list